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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
2.12
Human Site:
T1455
Identified Species:
3.59
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
T1455
R
A
Q
A
R
A
P
T
P
L
P
P
L
L
P
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
D1276
P
A
L
P
A
V
E
D
S
E
A
T
E
T
S
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
D209
T
L
P
V
G
E
L
D
A
V
S
P
I
V
N
Dog
Lupus familis
XP_543382
1925
209302
A1458
R
A
Q
T
R
A
P
A
Q
L
P
P
L
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
P1518
R
A
Q
P
R
P
P
P
Q
L
P
P
L
L
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
T280
Y
T
P
Q
S
Q
G
T
P
L
T
P
R
L
G
Chicken
Gallus gallus
Q5F3P8
2008
223067
A1561
S
V
L
L
S
P
E
A
P
V
G
A
S
I
L
Frog
Xenopus laevis
Q66J90
1938
216239
E1498
L
S
E
E
S
E
C
E
F
T
K
G
Q
L
P
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
G1386
A
A
S
S
P
F
P
G
P
P
L
P
T
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
Q1225
Y
S
E
G
G
S
S
Q
A
S
Q
A
S
Q
V
Honey Bee
Apis mellifera
XP_395451
1406
159180
S991
L
R
L
N
S
Q
Q
S
P
K
N
S
Q
A
S
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
H1092
S
I
R
A
H
E
Y
H
P
F
T
T
E
H
C
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
E1415
E
V
A
K
K
K
L
E
K
A
P
S
R
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
K898
D
N
T
K
P
K
K
K
A
K
A
K
K
K
S
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
6.6
6.6
80
N.A.
73.3
N.A.
N.A.
33.3
6.6
13.3
26.6
N.A.
0
6.6
13.3
6.6
P-Site Similarity:
100
6.6
26.6
80
N.A.
73.3
N.A.
N.A.
33.3
20
26.6
33.3
N.A.
20
13.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
36
8
15
8
15
0
15
22
8
15
15
0
15
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
0
0
0
0
0
15
0
0
0
0
0
0
8
% D
% Glu:
8
0
15
8
0
22
15
15
0
8
0
0
15
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
8
8
0
0
0
0
0
% F
% Gly:
0
0
0
8
15
0
8
8
0
0
8
8
0
0
8
% G
% His:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
0
15
8
15
8
8
8
15
8
8
8
15
0
% K
% Leu:
15
8
22
8
0
0
15
0
0
29
8
0
22
36
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
0
0
0
0
8
0
0
0
8
% N
% Pro:
8
0
15
15
15
15
29
8
43
8
29
43
0
0
29
% P
% Gln:
0
0
22
8
0
15
8
8
15
0
8
0
15
8
0
% Q
% Arg:
22
8
8
0
22
0
0
0
0
0
0
0
15
0
0
% R
% Ser:
15
15
8
8
29
8
8
8
8
8
8
15
15
0
29
% S
% Thr:
8
8
8
8
0
0
0
15
0
8
15
15
8
8
0
% T
% Val:
0
15
0
8
0
8
0
0
0
15
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _